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. intolerance). Ibrutinib is The existing gold regular therapy for sufferers with relapsed/refractory disease, based upon the outcomes of quite a few stage I-III trials, a hundred and fifteen–119 but That is also altering for 2 key reasons: (i) an increasing proportion of sufferers now receive ibrutinib as frontline therapy; and (ii) several critical contenders have appeared in the final calendar year.
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